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There are 1,161 companies in the field of Biopharma on spotfolio that produce or deliver products, that utilize or research technologies or that are otherwise engaged in topics such as Drug, Clinical, Patients, Pharmaceutical, Research, Therapeutic, Treatment, Development .

Start-ups (201)

Early-stage companies (306)

Established companies (563)

The majority of these companies is located in the following countries.

United States (589)

United Kingdom (90)

China (59)

Canada (54)

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Evotec Evotec AG

established

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silico drug discovery - Proteomics and metabolomics - Bio-reagents - In vitro biology - In vivo pharmacology - Biomarkers - Antibody discovery Drug discovery ...

complications - Neurosciences - Oncology - Respiratory Therapeutic areas - Integrated drug discovery - EVT Execute alliances - Scientific publications - Resources ...

result This is a result This is a result - DE EN Integrated CMC EVT Execute Drug discovery services Biologics INDiGO Integrated CMC API capabilities Material ...

Manufacturing Integrated pre-clinical development Therapeutic areas Integrated drug discovery EVT Execute alliances Science pool Integrated Chemistry, Manufacturing ...

Chemistry, Manufacturing and Control capabilities fully support drug substance and drug product development and GMP manufacturing from FIH to Phase III ...

development activities, from laboratory to commercial scale for both API and drug product. Straightforward, continuous processes from API to pre-clinical

silico drug discovery - Proteomics and metabolomics - Bio-reagents - In vitro biology - In vivo pharmacology - Biomarkers - Antibody discovery Drug discovery ...

complications - Neurosciences - Oncology - Respiratory Therapeutic areas - Integrated drug discovery - EVT Execute alliances - Scientific publications - Resources ...

result This is a result This is a result - DE EN Integrated drug discovery EVT Execute Drug discovery services Biologics INDiGO Integrated CMC Integrated ...

pre-clinical development Therapeutic areas Integrated drug discovery EVT Execute alliances Science pool Integrated drug discovery Evotec offers all the relevant ...

capabilities required to support drug discovery projects from target identification through to IND submission and beyond, but integrated drug discovery is much more ...

also offers partially or fully integrated drug discovery support to its partners by blending extensive drug discovery knowledge and experience, expert

Thermosome

early-stage

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solution A delivery strategy exploiting the intravascular drug release for 10 to 15 fold higher local drug concentrations © Thermosome Through our proprietary ...

proprietary thermosensitive liposomal (TSL) delivery technology, biocompatible drug-loaded nanocarriers – so-called Thermosomes – can be created which release ...

encapsulated drug at normal body temperature (around 37°C) and thereby prevent an unwanted drug-target interaction with healthy tissue. The drug load is rapidly ...

application of mild heat, such as microwave or ultrasound. Different to traditional drug delivery systems, where the accumulation of the carrier system itself in ...

mechanism of action of TSLs (such as Thermosomes) is called intravascular drug release and was first published by Manzoor, Lindner et al. in Cancer Research ...

Research in 2012. As our Thermosomes rapidly release their encapsulated drug intravenously, our technology avoids the rate-limiting steps of current advanced

clinician-controlled drug delivery through TSL nanoparticles as delivery vehicle To overcome the shortcomings of traditional drug delivery strategies using ...

stimuli-responsive drug delivery techniques in the past decades. According to a review article in Nature Materials from 2013 by Mura et al., several of these drug delivery ...

insufficient biocompatibility, inadequate sensitivity to the used trigger for drug release, problems in scaling up and/or complexity of their architectural ...

promising candidate. The concept of TSL-based drug delivery TSLs are exploiting the intravascular drug release by combining heat-triggerable nanocarriers ...

as a tumor). The unique advantage of combining these technologies is that drug deposition in the diseased tissue could be externally controlled spatially ...

phospholipid composition, the shell becomes porous and releases the encapsulated drug in high concentrations. © Thermosome Current state-of-the-art TSL Several

KSQ Therapeutics KSQ Therapeutics, Inc.

early-stage

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- About Us - CRISPRomics® + - CRISPRomics® - Target & Drug Discovery - Key Enabling Discoveries Timeline - Publications - Pipeline - News - People + ...

for PD 1 Resistant Solid Tumors – Company’s Pipeline Spans Three Oncology Drug Categories: Adoptive T‑Cell Therapies, Immuno-Oncology Monotherapies and ...

Therapies – – Proprietary CRISPRomics™ Discovery Engine Has Yielded 12 Oncology Drug Discovery Programs in 12 Months – CAMBRIDGE, Mass. – September 28, 2018 ...

Series C financing to advance oncology drug candidates generated from the company’s proprietary CRISPRomics™ drug discovery engine into clinical studies ...

KSQ will advance its first drug program into the clinic within the next 18 months and up to three additional oncology drug programs into IND-enabling studies ...

studies. The company’s first drug program is a modified adoptive T-cell immunotherapy which has shown efficacy in multiple animal models of PD-1 resistance

- About Us - CRISPRomics® + - CRISPRomics® - Target & Drug Discovery - Key Enabling Discoveries Timeline - Publications - Pipeline - News - People + ...

Industry Leader Brings Expertise in Medical, Clinical and Regulatory Affairs in Drug Development – Cambridge, Mass., September 25, 2018 – KSQ Therapeutics today ...

includes serving in leadership roles in the U.S. Food and Drug Administration’s (FDA’s) Center for Drug Evaluation and Research (CDER) and in medical affairs ...

industry and regulatory knowledge for advancing innovative medicines through the drug development process, which will be a valuable asset to KSQ as we advance ...

to become part of the pioneering drug development approach at KSQ, which has the potential to improve the quality of drug targets and, therefore, offer the ...

the potential to shorten drug development timelines and increase the pace of bringing meaningful medicines to patients,” said Dr. Moscicki. “I look forward

Spinnaker Biosciences

established

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dimensions of a drug of interest. This provides a protective cage for the drug, and it yields control over the rate of release of the drug and the rate ...

dissolution of the particles. Drug-infused, resorbable biomaterial for sustained drug release Pores can be finely tuned to a specific drug release profile Ability ...

size to molecular size of drug Pores can be customized for drugs with different properties Pores can accommodate several drug types simultaneously Advantages ...

degradation polymers can change the pH of local micro-environment affecting drug stability resulting in a loss of activity. Polymers are often associated ...

pSi drug loading process is aqueous based. Polymers are cast from organic solvents that are often not compatible with proteins. Safe Sustained Drug Delivery

10, 3505–3512 (2014). 3. Hou, H. et al. Tunable sustained intravitreal drug delivery system for daunorubicin using oxidized porous silicon. J. Control ...

et al. Hydrosilylated porous silicon particles function as an intravitreal drug delivery system for daunorubicin. J. Ocul. Pharmacol. Ther. Off. J. Assoc ...

Intraocular Drug Delivery System. Invest. Ophthalmol. Vis. Sci. 54, 1268–1279 (2013). 7. Wu, E. C. et al. Real-time Monitoring of Sustained Drug Release using ...

L., Freeman, W. R. & Sailor, M. J. Porous silicon in drug delivery devices and materials. Adv. Drug Deliv. Rev. 60, 1266–1277 (2008). 10. Cheng, L. et ...

photonic crystals. Br. J. Ophthalmol. 92, 705–711 (2008). Safe Sustained Drug Delivery using Nanoporous Silicon Particles Web Hosting powered by Network

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phasic oral drug delivery - in-vivo opportunities and challenges • What mechanisms define complex oral drug delivery profiles? • The release of drug from complex ...

complex oral drug delivery systems should be entirely independent of patient factors such as pH and GI motility. • Case study: OralogiKTM - an erosion based ...

timed-release OralogiK™ technology £2M backing from Archangels and SIB for UK drug delivery company BDD Recent Posts Another success for BDD's patented OralogiK™ ...

aspirin tablet formulations compared to ibu Releasing The Potential: How Novel Drug Delivery Technologies Can Deliver Competitive Advantage In T BDD appoints ...

BDD at 4th Annual Formulation & Drug Delivery Congress. 8-9th May - London. £2M backing from Archangels and SIB for UK drug delivery company BDD BDD Chairman

Where's my drug? Once you dose your drug in man, can you really be sure where it is at any given time? PK data is invaluable for showing drug concentrations ...

versatile technology used to investigate the in-vivo performance of your drug or product. This non-invasive imaging technique allows us to follow the fate ...

timed-release OralogiK™ technology £2M backing from Archangels and SIB for UK drug delivery company BDD Recent Posts Another success for BDD's patented OralogiK™ ...

aspirin tablet formulations compared to ibu Releasing The Potential: How Novel Drug Delivery Technologies Can Deliver Competitive Advantage In T BDD appoints ...

BDD at 4th Annual Formulation & Drug Delivery Congress. 8-9th May - London. £2M backing from Archangels and SIB for UK drug delivery company BDD BDD Chairman ...

Why is product life cycle management in Pharma so important? Where's my drug? Meet Richard at DDL 2015 Archive - February 2020 (1) - June 2019 (1)

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